Description
High Quality Anti-Cancer Medicine Grade Paclitaxel Purity 99% CAS 33069-62-4
Description
High Quality Anti-Cancer Medicine Grade Paclitaxel Purity 99% CAS 33069-62-4
- Product description
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Product name Paclitaxel CAS No. - 33069-62-4
Molecular Formula - C47H51NO14
Molecular weight 853.92 Grade Standard Medicine Grade COA Avaliable - Product introduction
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Paclitaxel is a potent anticancer medication which can promote microtubule (MT) assembly, inhibit MT depolymerization, and change MT dynamics required for mitosis and cell proliferation. Paclitaxel is a natural secondary metabolite extracted from the bark of Taxus chinensis, which has good antitumor effect. It is commonly used in the treatment of ovarian cancer, uterine cancer and breast cancer.
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- Product application
An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanc ed forms of Kaposi’s sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it ‘taxol’. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to ‘paclitaxel’ and the BMS compound is sold under the trademark ‘TAXOL’. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent. A newer formulation, in which paclitaxel is bound to albumin.
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