GMP Medicine Grade Purity 99% Chlorthalidone CAS 77-36-1

GMP Factory Supply Good Quality Chlorthalidone CAS 77-36-1 Raw Powder High Purity 99%

• Product description

• Product name	Chlortalidone
  CAS No.	77-36-1
  Molecular Formula	C14H11ClN2O4S
  Molecular weight	338.77
  Grade Standard	Medicine Grade
  COA	Avaliable

• Product introduction

• Chloropralidone tables are white. Oral absorption is incomplete. It mainly binds to intracellular carbonic anhydrase, but rarely binds to plasma protein. In severe anemia, it binds to plasma protein (mainly albumin). Oral administration took effect for 2 hours, the peak time was 2 hours, and the duration of action was 24 ~ 72 hours. T1 / 2 is 35 ~ 50 hours. The half-life and action duration of this drug are significantly longer than those of other thiazides. The reason is that this drug is mainly combined with erythrocyte carbonic anhydrase, so its excretion and metabolism are slow. It is mainly excreted from the urine in its original form, and some are metabolized in the body and excreted by extrarenal routes. The biliary tract is not the main excretion route.

• Product Function

1. Edema disease: excrete excessive sodium and water in the body, reduce the volume of extracellular fluid and eliminate edema.
2. Hypertension. It can be used alone or in combination with other antihypertensive drugs, mainly for the treatment of essential hypertension.
3. Central or renal diabetes insipidus.
4. Nephrolithiasis. It is mainly used to prevent the formation of stones containing calcium salts