Description
99% Purity White Sunifiram Nootropics Powder CAS 314728 85 3
Description
| Product Name: | Sunifiram | Other Name: | 1-(4-Benzoyl-1-piperazinyl)-1-propanone |
|---|---|---|---|
| CAS No: | 314728-85-3 | MF: | C14H18N2O2 |
| MW: | 246.3 | Purity: | 99% Min |
| Shelf Life: | 2 Years | Application: | Pharmaceutical API |
| Sample: | Available | Storage: | Cool And Dry Place |
| High Light: |
Sunifiram Nootropic CAS 314728 85 3, Nootropics Powder CAS 314728 85 3, 99% Purity Sunifiram Nootropic |
||
99% Purity White Powder Nootropics Powder CAS 314728-85-3 Sunifiram
Product Introduction
| Name | SunifiraM |
| English synonyms | 1-(4-Benzoyl-1-piperazinyl)-1-propanone |
| CAS Number | 314728-85-3 |
| Molecular formula | C14H18N2O2 |
| Molecular weight | 246.3 |
| EINECS number | 1312995-182-4 |
Product Description
| Melting point | / |
| Boiling point | 442.0±38.0 °C(Predicted) |
| Density | 1.154±0.06 g/cm3 (20 ºC 760 Torr) |
| Solubility | H2O: soluble24mg/mL |
| Storage | Cool and dry place |
| Acidity coefficient (pKa) | 0.08±0.70(Predicted) |
Product Function
Sunifiram (DM235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency thanpiracetam. A number of related compounds are known, the best known being unifiram (DM-232).
This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycinebinding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation. Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.
