99% Purity Anti-Cancer Drug 2.0% BHT/No BHT Everolimus Powder CAS 159351-69-6

99% Purity Anti-Cancer Drug 2.0% BHT/No BHT Everolimus Powder CAS 159351-69-6

• Product description

• Product name	Everolimus
  CAS No.	159351-69-6
  Molecular Formula	C53H83NO14
  Molecular weight	958.22
  Grade Standard	Medicine Grade
  COA	Avaliable

• Product introduction

• Everolimus is a derivative of Rapamycin(sirolimus), and works similarly to Rapamycin as an mTOR(mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors, Everolimus takes effect solely on the mTORC1 protein and not on the mTORC2 protein. In transplantation medicine, it is marketed under the trade names Zortress(USA) and Certican(Europe). It has been also used for the treatment of tumors, being marketed as Afinitor(general tumours) and Votubia(tumours as a result of TSC) in oncology.

• Product function

Everolimus is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an inhibitor of mammalian target of rapamycin (mTOR). It is currently used as an immunosuppressant to prevent rejection of organ transplants and in the treatment of renal cell cancer and other tumours. Much research has also been conducted on everolimus and other mTOR inhibitors as targeted therapy for use in a number of cancers.